Turning human genetic data into the actionable evidence that moves decisions
for pharma R&D biotech life science investors CROs
The Genetic Edge
Human genetic evidence is one of the most powerful tools available to de-risk drug targets, yet its potential remains largely untapped in early-stage R&D. Unlike animal models or observational data, human genetics delivers causal evidence directly from human biology, at the stage where it changes decisions. For the first time, the data and tools now exist to leverage human genetics rigorously and at scale across therapeutic areas.
90%
of Phase II failures are driven by insufficient evidence that the target causally drives disease in humans.
150k+
human genetic datasets on clinical outcomes across therapeutic areas and molecular traits available for causal analyses
3 Weeks
from target and indication to a decision-ready evidence report
MendelyticsTM: Rigour at Speed
Through our MendelyticsTM platform, our team delivers deep genetic intelligence in weeks, without compromising the analytical rigor your decisions depend on. We maintain scientific integrity and transparency. Every output comes with full methodological transparency, so you understand not just what we found, but why you can trust it.
Use Cases
Whether you’re a biotech building a programme, a pharma team assessing an asset, an investor deciding whether to back a programme, or a CRO strengthening the evidence behind your client work, AquilaGen delivers the evidence layer specific to your question.
De-risking before committing capital
Genetic evidence at every stage of your journey
Faster, better-informed decisions on targets and assets.
Extending your scientific offering
Add genetics-driven target validation to your preclinical and clinical workflows, strengthening the scientific case you deliver to pharma clients.
Advance drug target research
Independent causal analysis for hypothesis testing, methodological support for grant applications and postgraduate research, and training courses in causal inference methods.
Your Genetics Team
AquilaGen is your dedicated genetics team. We embed analytical rigour, clinical expertise and commercial fluency into your programme, translating genetic findings into the decisions that matter most: which target to progress, which indication to prioritize, and where the human evidence is strong enough to act on. Our cross-disciplinary team brings together statistical genetics, clinical medicine, and drug development expertise to systematically integrate causal human evidence across the life sciences ecosystem.
Capabilities
From foundational target validation to upstream discovery, every analysis is designed to inform a decision, not just add data.
Tier 1
Foundational evidence
Validation
Tier 2
Deeper intelligence
Advanced Characterization
Tier 3
Upstream intelligence
Discovery
News
Resources
